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Theory Manual Version 3.6
 Subsection 3.4.7: Chemical Reactions Up Subsection 3.4.7: Chemical Reactions Subsubsection 3.4.7.2: Updating Solid-Bound Molecule Concentrations 

3.4.7.1 Virtual Work and Linearization

The contribution to due to chemical reactions is given by , where The linearization of along a solid displacement increment is where Currently, is assumed to be independent of in FEBio; it follows that the linearization along the effective fluid pressure increment is Finally, the linearization along a concentration increment is
The discretized form of these expressions is given by where Similarly, where Then, where Finally, where
 Subsection 3.4.7: Chemical Reactions Up Subsection 3.4.7: Chemical Reactions Subsubsection 3.4.7.2: Updating Solid-Bound Molecule Concentrations